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Home > Research > Abstracts: Treatment

 

Treatment

 

RX, Controlled Data

Pregabalin | Duloxetine | Milnacipran | Pramipexole | Sodium Oxybate

 

Gabapentin

Tramadol | Fluoxetine/Amitriptyline | Cyclobenzaprine | Growth Hormone/Pyridostigmine | Synthetic Cannaboids

 

RX, Uncontrolled Data

Pindolol | Venlafaxine

 

Over-theCounter (OTC) Medications

Acetyl L-Carnitine | Melatonin

 

Complementary and Alternative Medicine (CAM) Therapies

Cranial Electrotherapy | Heart Rate Variability | Biofeedback | Exercise

 

 

Treatment: RX, Controlled Data

 

Pregabalin

Fibromyalgia relapse evaluation and efficacy for durability of meaningful relief (FREE DOM ): a 6-month, doubleblind, placebo-controlled trial with pregabalin

Pain. 2008 Jun;136(3):419-31.

Crofford L J, Mease PJ, S impson SL , Young JP Jr, Martin SA , Haig GM , Sharma U...[ view ]

 

A 14-week, Randomized, Double-Blinded, Placebo-Controlled Monotherapy Trial of Pregabalin in Patients With Fibromyalgia

J Pain. 2008 Sept; 9(9): 792-805.
Arnold LM, Russell IJ, Diri EW, Duan WR, Young, Jr JP, Sharma U, Martin SA, Barrett JA, Haig G...[ view ]

 

Duloxetine

Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: Results from a 6-month, randomized, double-blind, placebo-controlled, fixed-dose trial

Pain. 2008 Jun;136(3):432-44.
Russell I J, Mease PJ, Smith TR, Kajdasz DK ,Wohlreich MM , Detke M J, Walker D J, Chappell AS , Arnold LM...[ view ]

 

A randomized, double-blind, placebo-controlled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder

Pain. 2005 Dec 15;119(1-3):5-15.
Arnold LM, Rosen A, Pritchett YL, D’Souza DN, Goldstein DJ, Iyengar S, Wernicke JF...[ view ]

 

A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder

Arthritis Rheum. 2004 Sep;50(9):2974-84. 
Arnold LM, Lu Y, Crofford LJ, Wohlreich M, Detke MJ, Iyengar S, Goldstein DJ...[ view ]

 

Milnacipran

Efficacy of milnacipran in patients with fibromyalgia

J Rheumatol. 2005 Oct;32(10):1975-85. 
Gendreau RM, Thorn MD, Gendreau JF, Kranzler JD, Ribeiro S, Gracely RH, Williams DA, Mease PJ, McLean SA, Clauw DJ...[ view ]

 

Pramipexole

A randomized, double-blind, placebo-controlled trial of pramipexole, a dopamine  agonist, in patients with fibromyalgia receiving concomitant medications 

Arthritis Rheum. 2005 Aug;52(8):2495-505.

Holman AJ, Myers RR...[ view ]  

 

Safety and efficacy of the dopamine agonist, pramipexole, on pain score for refractory fibromyalgia

Arthritis Rheum 2000;43 Suppl:A1599.

Holman AJ...[ view ]   

 

Sodium Oxybate

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multi-Center Trial Comparing the Effects of Orally Administered Xyrem® (Sodium Oxybate) with Placebo for the Treatment of Fibromyalgia

Pain Medicine. 2006; 7(2):170209.
Wood PB...[ view ]

 

The effects of sodium oxybate on clinical symptoms and sleep patterns in patients with fibromyalgia

J Rheumatol. 2003 May;30(5):1070-4.
Scharf MB, Baumann M, Berkowitz DV...[ view ]

 

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Treatment: Gabapentin 

 

Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial

Arthritis Rheum. 2007 Apr;56(4):1336-44.
Arnold LM, Goldenberg DL, Stanford SB, Lalonde JK, Sandhu HS, Keck PE Jr, Welge JA, Bishop F, Stanford KE, Hess EV, Hudson JI. ..[ view ]   

 

Fluoxetine/ Amitriptyline

A randomized, double-blind crossover trial of fluoxetine and amitriptyline in the treatment of fibromyalgia

Arthritis Rheum. 1996 Nov;39(11):1852-9.
Goldenberg D, Mayskiy M, Mossey C, Ruthazer R, Schmid C...[ view ]

 

Cyclobenzaprine

Treatment of fibromyalgia with cyclobenzaprine: A meta-analysis

Arthritis Rheum. 2004 Feb 15;51(1):9-13.
Tofferi JK, Jackson JL, O’Malley PG...[ view ]

 

Growth Hormone/Pyridostigmine

A randomized, double-blind, placebo-controlled study of growth hormone in the treatment of fibromyalgia

Am J Med. 1998 Mar;104(3):227-31.
Bennett RM, Clark SC, Walczyk J...[ view ]

 

A combination of 6 months of treatment with pyridostigmine and triweekly exercise fails to improve insulin-like growth factor-Ilevels in fibromyalgia, despite improvement in the acute growth hormone response to exercise

J Rheumatol. 2007 May;34(5):1103-11.
Jones KD, Deodhar AA, Burckhardt CS, Perrin NA, Hanson GC, Bennett RM...[ view ]

 

Synthetic Cannaboids

Nabilone for the treatment of pain in fibromyalgia

J Pain. 2008 Feb;9(2):164-73. 
Skrabek R Q, Galimova L , Ethans K , Perry D...[ view ]

 

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Treatment: RX, Uncontrolled Data

 

Pindolol

Open trial of pindolol in the treatment of fibromyalgia

Ann Pharmacother. 2005 Nov;39(11):1812-6.

Wood PB, Kablinger AS, Caldito GS...[ view ]

 

Venlafaxine

Venlafaxine treatment of fibromyalgia

Ann Pharmacother. 2003 Nov;37(11):1561-5.
Sayar K, Aksu G, Ak I, Tosun M...[ view ]

 

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Treatment: Over-theCounter (OTC) Medications

 

Alcar

Double-blind, multicenter trial comparing acetyl l-carnitine with placebo in the treatment of fibromyalgia patients

Clin Exp Rheumatol. 2007 Mar-Apr;25(2):182-8. 
Rossini M, Di Munno O, Valentini G, Bianchi G, Biasi G, Cacace E, Malesci D, La Montagna G, Viapiana O, Adami S...[ view ]

 

Melatonin

The effect of melatonin in patients with fibromyalgia: a pilot study

Clin Rheumatol. 2000;19(1):9-13.
Citera G, Arias MA, Maldonado-Cocco JA, Lázaro MA, Rosemffet MG, Brusco LI, Scheines EJ, Cardinalli DP...[ view ]

 

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Treatment: Complementary and Alternative Medicine (CAM) Therapies

 

Treatment of cervical myelopathy in patients with the fibromyalgia syndrome: outcomes and implications

Eur Spine J. 2007 Apr 11.
Heffez DS, Ross RE, Shade-Zeldow Y, Kostas K, Morrissey M, Elias DA, Shepard A...[ view ]

 

Cranial Electrotherapy Stimulation

The treatment of fibromyalgia with cranial electrotherapy stimulation

J Clin Rheumatol. 2001 Apr;7(2):72-8.  
Lichtbroun AS, Raicer MM, Smith RB...[ view ]

 

The Effect of Cranial Electrotherapy Stimulation (CES) on Pain Associated with Fibromyalgia

The Internet Journal of Anesthesiology. 2004; 8(2).   
Cork RC, Wood PB, Ming N, Shepherd C, Eddy J, Price L...[ view

 

Heart Rate Variability

A pilot study of the efficacy of heart rate variability (HRV) biofeedback in patients with fibromyalgia

Appl Psychophysiol Biofeedback. 2007 Mar;32(1):1-10.
Hassett AL , Radvanski D C, Vaschillo EG , Vaschillo B ,Sigal LH , Karavidas MK , Buyske S , Lehrer PM...[ view ]

 

Exercise

Self-assessed physical function levels of women with fibromyalgia: a national survey

Arthritis Res Ther. 2008 Aug 8;10(4):211.
Jones J, Rutledge DN, Jones KD, Matallana L, Rooks DS...[ view ]

 

Exercise-based motivational interviewing for female patients with fibromyalgia: a case series

Clin Rheumatol. 2007 N ov;26(11):1843-9.
Ang D , Kesavalu R , Lydon JR, Lane KA , Bigatti S...[ view ]

 

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